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Q Which of the following is a combined 5-HT4 agonist and D2 antagonist?
A. Metoclopramide
B. Domperidone
C. Erythromycin
D. Octreotide

Explanation
Correct Answer: A. Metoclopramide
[Harrison’s 18th Ed. 304]
Metoclopramide is a combined 5-HT4 agonist & D2 antagonist. Domperidone is a D2 antagonist.
Erythromycin increases gastroduodenal motility by action on receptors for motilin. Somatostatin analogue octreotide induces propagative small intestinal motor complexes.