Q About cetirizine all are true except
A. Good CNS penetration
B. Second generation anti histamine
C. Metabolite of hydroxyzine
D. Inhibits release of histamine
Explanation
Cetirizine
Second generation anti histamine with marked affinity for peripheral H1 receptors. It is a metabolite of hydroxyzine. Penetrates CNS poorly. It is non arrythmogenic. It inhibits release of histamine from mast cells.
A. Good CNS penetration B. Second generation anti histamine C. Metabolite of hydroxyzine D. Inhibits release of histamine Explanation
Cetirizine
Second generation anti histamine with marked affinity for peripheral H1 receptors. It is a metabolite of hydroxyzine. Penetrates CNS poorly. It is non arrythmogenic. It inhibits release of histamine from mast cells.