Q Prostaglandins have effects on a variety of tissues. The different prostaglandins may have different effects. Which of the following statements is not correct?
A. he human arteriolar smooth muscle is relaxed by PGE2 and PGI2 whereas TXA2 and PGF2α cause vasoconstriction
B. PGE1 and PGI2 inhibit platelet aggregation whereas TXA2 facilitate aggregation
C. PGE2 has marked oxytocic action while PGF2α has tocolytic action
D. PGE2 is a bronchodilator whereas PGF2α is a bronchoconstrictor
Explanation
Correct Answer: C.PGE2 has marked oxytocic action while PGF2a has tocolytic action
(Ref: KDT 6/e p181)
• PGE2 mainly causes softening of cervix and is utilized for cervical ripening whereas PGF2a is an oxytocic agent and
can be utilized for the induction of abortion.
A. he human arteriolar smooth muscle is relaxed by PGE2 and PGI2 whereas TXA2 and PGF2α cause vasoconstriction B. PGE1 and PGI2 inhibit platelet aggregation whereas TXA2 facilitate aggregation C. PGE2 has marked oxytocic action while PGF2α has tocolytic action D. PGE2 is a bronchodilator whereas PGF2α is a bronchoconstrictor Explanation
Correct Answer: C.PGE2 has marked oxytocic action while PGF2a has tocolytic action
(Ref: KDT 6/e p181)
• PGE2 mainly causes softening of cervix and is utilized for cervical ripening whereas PGF2a is an oxytocic agent and
can be utilized for the induction of abortion.